MolNFT v1 · #254284 · protein
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A5FQC0)
A5FQC0: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A5FQC0)”. 5 pockets (best druggability 0.81). MolNFT v1 #254284 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A5FQC0
- Type
- protein
- Length
- 858 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x46EfCa788d03A3e879DAcDb96552AB8Bbc7e20b3
- Molecule
- DNA mismatch repair protein muts
- UniProt
- A5FQC0
- Pockets
- 5 · best druggability 0.81
Structure
1 distinct chain · 46% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein muts | protein | 858 | 46% helix, 19% strand | A5FQC0 |
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 963 | 0.81 | 0.83 | 106 | empty |
| 2 | 286 | 0.50 | 0.73 | 33 | empty |
| 3 | 118 | 0.43 | 0.77 | 20 | empty |
| 4 | 108 | 0.38 | 0.75 | 15 | empty |
| 5 | 77 | 0.30 | 0.73 | 20 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A5FQC0
- Elsewhere: UniProt A5FQC0 · AlphaFold DB A5FQC0
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