MolNFT v1 · #254270 · protein
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q8XL87)
Q8XL87: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q8XL87)”. 11 pockets (best druggability 0.76). MolNFT v1 #254270 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8XL87
- Type
- protein
- Length
- 909 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x738c1929c69B751bD0Be0B962D9bac20B631aAc6
- Molecule
- DNA mismatch repair protein muts
- UniProt
- Q8XL87
- Pockets
- 11 · best druggability 0.76
Structure
1 distinct chain · 47% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein muts | protein | 909 | 47% helix, 18% strand | Q8XL87 |
Pockets
11 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 787 | 0.76 | 0.80 | 83 | empty |
| 2 | 155 | 0.59 | 0.83 | 25 | empty |
| 3 | 272 | 0.53 | 0.75 | 29 | empty |
| 4 | 219 | 0.52 | 0.77 | 25 | empty |
| 5 | 234 | 0.50 | 0.75 | 39 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8XL87
- Elsewhere: UniProt Q8XL87 · AlphaFold DB Q8XL87
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