MolNFT v1 · #254260 · protein
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A5I2S2)
A5I2S2: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A5I2S2)”. 10 pockets (best druggability 0.76). MolNFT v1 #254260 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A5I2S2
- Type
- protein
- Length
- 932 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x362a6d063b1B7E1B6EfD3A9A7CA3612e3FE037AA
- Molecule
- DNA mismatch repair protein muts
- UniProt
- A5I2S2
- Pockets
- 10 · best druggability 0.76
Structure
1 distinct chain · 44% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein muts | protein | 932 | 44% helix, 17% strand | A5I2S2 |
Pockets
10 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 764 | 0.76 | 0.80 | 78 | empty |
| 2 | 391 | 0.67 | 0.80 | 42 | empty |
| 3 | 435 | 0.63 | 0.77 | 51 | empty |
| 4 | 387 | 0.58 | 0.75 | 33 | empty |
| 5 | 81 | 0.50 | 0.83 | 16 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A5I2S2
- Elsewhere: UniProt A5I2S2 · AlphaFold DB A5I2S2
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