MolNFT v1 · #254257 · protein
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A6LWJ5)
A6LWJ5: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A6LWJ5)”. 6 pockets (best druggability 0.79). MolNFT v1 #254257 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A6LWJ5
- Type
- protein
- Length
- 928 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x35612D34a32C306CA4fc1edA9360D1F717e25950
- Molecule
- DNA mismatch repair protein muts
- UniProt
- A6LWJ5
- Pockets
- 6 · best druggability 0.79
Structure
1 distinct chain · 43% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein muts | protein | 928 | 43% helix, 18% strand | A6LWJ5 |
Pockets
6 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 888 | 0.79 | 0.82 | 82 | empty |
| 2 | 474 | 0.63 | 0.76 | 45 | empty |
| 3 | 212 | 0.56 | 0.79 | 22 | empty |
| 4 | 127 | 0.51 | 0.80 | 28 | empty |
| 5 | 106 | 0.38 | 0.75 | 26 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A6LWJ5
- Elsewhere: UniProt A6LWJ5 · AlphaFold DB A6LWJ5
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