MolNFT v1 · #254242 · protein
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A4SFT1)
A4SFT1: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A4SFT1)”. 6 pockets (best druggability 0.75). MolNFT v1 #254242 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A4SFT1
- Type
- protein
- Length
- 874 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xBeF036C04BE8b62aF43C82A9ec62223aAa892154
- Molecule
- DNA mismatch repair protein muts
- UniProt
- A4SFT1
- Pockets
- 6 · best druggability 0.75
Structure
1 distinct chain · 46% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein muts | protein | 874 | 46% helix, 19% strand | A4SFT1 |
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1077 | 0.75 | 0.78 | 79 | empty |
| 2 | 381 | 0.66 | 0.80 | 38 | empty |
| 3 | 406 | 0.57 | 0.74 | 38 | empty |
| 4 | 151 | 0.44 | 0.75 | 23 | empty |
| 5 | 83 | 0.39 | 0.77 | 15 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A4SFT1
- Elsewhere: UniProt A4SFT1 · AlphaFold DB A4SFT1
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