MolNFT v1 · #254215 · protein

AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A1V5I2)

A1V5I2: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A1V5I2)”. 8 pockets (best druggability 0.69). MolNFT v1 #254215 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: A1V5I2
Type: protein
Length: 891 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x1ca26b2054BD7B7ddbC95b4914Ca7303754fF64e
Molecule: DNA mismatch repair protein muts
UniProt: A1V5I2
Pockets: 8 · best druggability 0.69

Structure

1 distinct chain · 47% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA mismatch repair protein muts	protein	891	47% helix, 19% strand	A1V5I2

Pockets

8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	606	0.69	0.78	66	empty
2	651	0.68	0.77	34	empty
3	353	0.58	0.77	44	empty
4	147	0.44	0.76	23	empty
5	80	0.40	0.78	16	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A1V5I2
Elsewhere: UniProt A1V5I2 · AlphaFold DB A1V5I2

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