MolNFT v1 · #254213 · protein
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A2SAW7)
A2SAW7: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A2SAW7)”. 8 pockets (best druggability 0.72). MolNFT v1 #254213 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A2SAW7
- Type
- protein
- Length
- 891 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x378a28002909c2509a47F088Dee431D1ba770530
- Molecule
- DNA mismatch repair protein muts
- UniProt
- A2SAW7
- Pockets
- 8 · best druggability 0.72
Structure
1 distinct chain · 47% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein muts | protein | 891 | 47% helix, 19% strand | A2SAW7 |
Pockets
8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 669 | 0.72 | 0.79 | 74 | empty |
| 2 | 645 | 0.68 | 0.76 | 34 | empty |
| 3 | 300 | 0.58 | 0.77 | 46 | empty |
| 4 | 147 | 0.43 | 0.75 | 22 | empty |
| 5 | 87 | 0.40 | 0.78 | 17 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A2SAW7
- Elsewhere: UniProt A2SAW7 · AlphaFold DB A2SAW7
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