MolNFT v1 · #254212 · protein

AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A3ML57)

A3ML57: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A3ML57)”. 10 pockets (best druggability 0.69). MolNFT v1 #254212 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: A3ML57
Type: protein
Length: 891 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x3d944850D26fB5c0d71746C4caCa5CD27831DE39
Molecule: DNA mismatch repair protein muts
UniProt: A3ML57
Pockets: 10 · best druggability 0.69

Structure

1 distinct chain · 47% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA mismatch repair protein muts	protein	891	47% helix, 19% strand	A3ML57

Pockets

10 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	628	0.69	0.77	32	empty
2	402	0.63	0.78	52	empty
3	337	0.61	0.78	33	empty
4	226	0.60	0.81	32	empty
5	106	0.43	0.78	21	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A3ML57
Elsewhere: UniProt A3ML57 · AlphaFold DB A3ML57

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