GL1X · GenesisL1 explorer

MolNFT v1 · #254197 · protein

AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A5VN83)

A5VN83: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A5VN83)”. 8 pockets (best druggability 0.80). MolNFT v1 #254197 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
A5VN83
Type
protein
Length
898 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x6Ee01E80b2Ce6582cc1bc5EE2465c8Eb47F96230
Molecule
DNA mismatch repair protein muts
UniProt
A5VN83
Pockets
8 · best druggability 0.80

Structure

1 distinct chain · 49% helix, 18% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ADNA mismatch repair protein mutsprotein89849% helix, 18% strandA5VN83

Pockets

8 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
19450.800.82106empty
24840.620.7632empty
31420.410.7428empty
4910.400.7818empty
5900.390.7714empty

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