MolNFT v1 · #254187 · protein
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A1R0M2)
A1R0M2: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A1R0M2)”. 11 pockets (best druggability 0.69). MolNFT v1 #254187 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A1R0M2
- Type
- protein
- Length
- 860 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x613050B9B793A1B5E9D1eC027267638DE6DbC575
- Molecule
- DNA mismatch repair protein muts
- UniProt
- A1R0M2
- Pockets
- 11 · best druggability 0.69
Structure
1 distinct chain · 49% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein muts | protein | 860 | 49% helix, 19% strand | A1R0M2 |
Pockets
11 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 524 | 0.69 | 0.79 | 57 | empty |
| 2 | 287 | 0.64 | 0.81 | 46 | empty |
| 3 | 181 | 0.50 | 0.77 | 26 | empty |
| 4 | 62 | 0.44 | 0.82 | 13 | empty |
| 5 | 115 | 0.40 | 0.76 | 17 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A1R0M2
- Elsewhere: UniProt A1R0M2 · AlphaFold DB A1R0M2
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