MolNFT v1 · #254171 · protein
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q8A334)
Q8A334: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q8A334)”. 7 pockets (best druggability 0.69). MolNFT v1 #254171 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8A334
- Type
- protein
- Length
- 862 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xf4ED13986579E8e227b3ED6c02276c648754EC27
- Molecule
- DNA mismatch repair protein muts
- UniProt
- Q8A334
- Pockets
- 7 · best druggability 0.69
Structure
1 distinct chain · 48% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein muts | protein | 862 | 48% helix, 19% strand | Q8A334 |
Pockets
7 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 549 | 0.69 | 0.78 | 47 | empty |
| 2 | 57 | 0.60 | 0.91 | 15 | empty |
| 3 | 463 | 0.58 | 0.74 | 47 | empty |
| 4 | 274 | 0.53 | 0.75 | 27 | empty |
| 5 | 288 | 0.52 | 0.75 | 30 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8A334
- Elsewhere: UniProt Q8A334 · AlphaFold DB Q8A334
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