MolNFT v1 · #254170 · protein
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (P49849)
P49849: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (P49849)”. 7 pockets (best druggability 0.75). MolNFT v1 #254170 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P49849
- Type
- protein
- Length
- 858 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x19acef217e76EAc343483083349ff33c90b60D4F
- Molecule
- DNA mismatch repair protein muts
- UniProt
- P49849
- Pockets
- 7 · best druggability 0.75
Structure
1 distinct chain · 46% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein muts | protein | 858 | 46% helix, 19% strand | P49849 |
Pockets
7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 717 | 0.75 | 0.80 | 64 | empty |
| 2 | 473 | 0.67 | 0.79 | 52 | empty |
| 3 | 361 | 0.57 | 0.75 | 31 | empty |
| 4 | 59 | 0.41 | 0.81 | 17 | empty |
| 5 | 86 | 0.39 | 0.78 | 17 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P49849
- Elsewhere: UniProt P49849 · AlphaFold DB P49849
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