MolNFT v1 · #254143 · protein
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (O66652)
O66652: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (O66652)”. 7 pockets (best druggability 0.76). MolNFT v1 #254143 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O66652
- Type
- protein
- Length
- 859 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x97EfFf2d74994e28D3b69b1503Bd9c292B2Df480
- Molecule
- DNA mismatch repair protein muts
- UniProt
- O66652
- Pockets
- 7 · best druggability 0.76
Structure
1 distinct chain · 49% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein muts | protein | 859 | 49% helix, 20% strand | O66652 |
Pockets
7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1013 | 0.76 | 0.78 | 79 | empty |
| 2 | 554 | 0.67 | 0.77 | 36 | empty |
| 3 | 573 | 0.67 | 0.77 | 60 | empty |
| 4 | 90 | 0.41 | 0.78 | 22 | empty |
| 5 | 84 | 0.37 | 0.75 | 15 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O66652
- Elsewhere: UniProt O66652 · AlphaFold DB O66652
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