MolNFT v1 · #254127 · protein
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A4SIL2)
A4SIL2: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A4SIL2)”. 9 pockets (best druggability 0.78). MolNFT v1 #254127 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A4SIL2
- Type
- protein
- Length
- 851 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x78Cc7f9BF18AF8279e492D45EE7Fe9d7cC6f6D07
- Molecule
- DNA mismatch repair protein muts
- UniProt
- A4SIL2
- Pockets
- 9 · best druggability 0.78
Structure
1 distinct chain · 48% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein muts | protein | 851 | 48% helix, 19% strand | A4SIL2 |
Pockets
9 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 616 | 0.78 | 0.84 | 70 | empty |
| 2 | 341 | 0.70 | 0.83 | 52 | empty |
| 3 | 448 | 0.66 | 0.78 | 31 | empty |
| 4 | 128 | 0.47 | 0.78 | 31 | empty |
| 5 | 109 | 0.45 | 0.79 | 18 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A4SIL2
- Elsewhere: UniProt A4SIL2 · AlphaFold DB A4SIL2
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