MolNFT v1 · #253901 · protein

AlphaFold monomer V2.0 prediction for DNA mismatch repair protein mutl (C1CBX8)

C1CBX8: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein mutl (C1CBX8)”. 5 pockets (best druggability 0.75). MolNFT v1 #253901 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: C1CBX8
Type: protein
Length: 649 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x362a6d063b1B7E1B6EfD3A9A7CA3612e3FE037AA
Molecule: DNA mismatch repair protein mutl
UniProt: C1CBX8
Pockets: 5 · best druggability 0.75

Structure

1 distinct chain · 37% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA mismatch repair protein mutl	protein	649	37% helix, 22% strand	C1CBX8

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	980	0.75	0.78	100	empty
2	252	0.73	0.87	33	empty
3	58	0.41	0.81	17	empty
4	90	0.40	0.78	17	empty
5	53	0.28	0.75	11	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt C1CBX8
Elsewhere: UniProt C1CBX8 · AlphaFold DB C1CBX8

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