MolNFT v1 · #253893 · protein
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein mutl (B2IS10)
B2IS10: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein mutl (B2IS10)”. 7 pockets (best druggability 0.75). MolNFT v1 #253893 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- B2IS10
- Type
- protein
- Length
- 649 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x5BeA89782341f98147F2D811B063F91F0aE7D7bF
- Molecule
- DNA mismatch repair protein mutl
- UniProt
- B2IS10
- Pockets
- 7 · best druggability 0.75
Structure
1 distinct chain · 36% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein mutl | protein | 649 | 36% helix, 21% strand | B2IS10 |
Pockets
7 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 100 | 0.75 | 0.95 | 20 | empty |
| 2 | 244 | 0.73 | 0.87 | 32 | empty |
| 3 | 328 | 0.63 | 0.79 | 42 | empty |
| 4 | 214 | 0.62 | 0.82 | 34 | empty |
| 5 | 191 | 0.59 | 0.81 | 39 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B2IS10
- Elsewhere: UniProt B2IS10 · AlphaFold DB B2IS10
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