MolNFT v1 · #253889 · protein
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein mutl (A2RGV3)
A2RGV3: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein mutl (A2RGV3)”. 11 pockets (best druggability 0.76). MolNFT v1 #253889 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A2RGV3
- Type
- protein
- Length
- 660 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xeE8B4A6A73707D0abde1030217eB534b4F77F2c6
- Molecule
- DNA mismatch repair protein mutl
- UniProt
- A2RGV3
- Pockets
- 11 · best druggability 0.76
Structure
1 distinct chain · 34% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein mutl | protein | 660 | 34% helix, 22% strand | A2RGV3 |
Pockets
11 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 426 | 0.76 | 0.85 | 49 | empty |
| 2 | 264 | 0.70 | 0.85 | 35 | empty |
| 3 | 403 | 0.66 | 0.79 | 54 | empty |
| 4 | 54 | 0.62 | 0.93 | 15 | empty |
| 5 | 76 | 0.50 | 0.84 | 17 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A2RGV3
- Elsewhere: UniProt A2RGV3 · AlphaFold DB A2RGV3
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