MolNFT v1 · #253830 · protein
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein mutl (Q8Z187)
Q8Z187: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein mutl (Q8Z187)”. 6 pockets (best druggability 0.71). MolNFT v1 #253830 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8Z187
- Type
- protein
- Length
- 618 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x58f6e67D5142B70031Af746651e7a6442367610c
- Molecule
- DNA mismatch repair protein mutl
- UniProt
- Q8Z187
- Pockets
- 6 · best druggability 0.71
Structure
1 distinct chain · 36% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein mutl | protein | 618 | 36% helix, 21% strand | Q8Z187 |
Pockets
6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 261 | 0.71 | 0.86 | 33 | empty |
| 2 | 161 | 0.48 | 0.77 | 30 | empty |
| 3 | 113 | 0.47 | 0.79 | 19 | empty |
| 4 | 108 | 0.44 | 0.77 | 14 | empty |
| 5 | 65 | 0.30 | 0.74 | 15 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8Z187
- Elsewhere: UniProt Q8Z187 · AlphaFold DB Q8Z187
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