MolNFT v1 · #253653 · protein
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein mutl (Q8XDN4)
Q8XDN4: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein mutl (Q8XDN4)”. 4 pockets (best druggability 0.72). MolNFT v1 #253653 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8XDN4
- Type
- protein
- Length
- 615 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x6DAA77C4263E74E745cA9c4D8E291e57e8991Cf5
- Molecule
- DNA mismatch repair protein mutl
- UniProt
- Q8XDN4
- Pockets
- 4 · best druggability 0.72
Structure
1 distinct chain · 36% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein mutl | protein | 615 | 36% helix, 21% strand | Q8XDN4 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 276 | 0.72 | 0.86 | 35 | empty |
| 2 | 164 | 0.50 | 0.78 | 14 | empty |
| 3 | 178 | 0.49 | 0.77 | 40 | empty |
| 4 | 105 | 0.43 | 0.78 | 21 | empty |
Compared structures
- 1NHI · Crystal structure of N-terminal 40KD mutl (LN40) complex with adpnp and one potassium · an experimental structure of the same protein · chain A against A, TM-score 0.54
- 1NHI · Crystal structure of N-terminal 40KD MutL (LN40) complex with ADPnP and one potassium · an experimental structure of the same protein · chain A against A, TM-score 0.54
- 1NHJ · Crystal structure of N-terminal 40KD MutL/A100P mutant protein complex with ADPnP and one… · an experimental structure of the same protein · chain A against A, TM-score 0.54
- 1NHJ · Crystal structure of N-terminal 40KD MUTL/A100P mutant protein complex with adpnp and one… · an experimental structure of the same protein · chain A against A, TM-score 0.54
- 1NHH · Crystal structure of N-terminal 40KD MutL protein (LN40) complex with ADPnP and one… · an experimental structure of the same protein · chain A against A, TM-score 0.53
- 1NHH · Crystal structure of N-terminal 40KD mutl protein (LN40) complex with adpnp and one… · an experimental structure of the same protein · chain A against A, TM-score 0.53
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8XDN4
- Elsewhere: UniProt Q8XDN4 · AlphaFold DB Q8XDN4
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