MolNFT v1 · #253649 · protein

AlphaFold monomer V2.0 prediction for DNA mismatch repair protein mutl (A7ZV39)

A7ZV39: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein mutl (A7ZV39)”. 5 pockets (best druggability 0.72). MolNFT v1 #253649 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: A7ZV39
Type: protein
Length: 615 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x159a74F8323b2EB2cC088ac2b0e2E49Cd847Cacd
Molecule: DNA mismatch repair protein mutl
UniProt: A7ZV39
Pockets: 5 · best druggability 0.72

Structure

1 distinct chain · 36% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA mismatch repair protein mutl	protein	615	36% helix, 21% strand	A7ZV39

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	282	0.72	0.86	35	empty
2	74	0.50	0.84	24	empty
3	136	0.47	0.78	22	empty
4	111	0.37	0.74	21	empty
5	51	0.26	0.74	13	empty

Compared structures

6E8E · Crystal structure of the escherichia COLI sliding clamp-mutl complex. · an experimental structure of the same protein · chain A against A, TM-score 0.23
6E8E · Crystal structure of the Escherichia coli sliding clamp-MutL complex. · an experimental structure of the same protein · chain A against A, TM-score 0.23

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A7ZV39
Elsewhere: UniProt A7ZV39 · AlphaFold DB A7ZV39

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.