MolNFT v1 · #253648 · protein
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein mutl (B8E280)
B8E280: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein mutl (B8E280)”. 4 pockets (best druggability 0.65). MolNFT v1 #253648 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- B8E280
- Type
- protein
- Length
- 572 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7a1388B6Aad67B04634A32f63b8A6D6005eab86c
- Molecule
- DNA mismatch repair protein mutl
- UniProt
- B8E280
- Pockets
- 4 · best druggability 0.65
Structure
1 distinct chain · 42% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein mutl | protein | 572 | 42% helix, 24% strand | B8E280 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 477 | 0.65 | 0.77 | 37 | empty |
| 2 | 385 | 0.61 | 0.77 | 42 | empty |
| 3 | 67 | 0.33 | 0.76 | 19 | empty |
| 4 | 63 | 0.30 | 0.75 | 14 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B8E280
- Elsewhere: UniProt B8E280 · AlphaFold DB B8E280
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