MolNFT v1 · #253615 · protein

AlphaFold monomer V2.0 prediction for DNA mismatch repair protein mutl (Q8KAX3)

Q8KAX3: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein mutl (Q8KAX3)”. 5 pockets (best druggability 0.76). MolNFT v1 #253615 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q8KAX3
Type: protein
Length: 624 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x78Cc7f9BF18AF8279e492D45EE7Fe9d7cC6f6D07
Molecule: DNA mismatch repair protein mutl
UniProt: Q8KAX3
Pockets: 5 · best druggability 0.76

Structure

1 distinct chain · 35% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA mismatch repair protein mutl	protein	624	35% helix, 21% strand	Q8KAX3

Pockets

5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	954	0.76	0.79	90	empty
2	253	0.69	0.85	38	empty
3	511	0.67	0.78	48	empty
4	96	0.37	0.75	15	empty
5	113	0.35	0.73	17	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8KAX3
Elsewhere: UniProt Q8KAX3 · AlphaFold DB Q8KAX3

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