MolNFT v1 · #248997 · protein
AlphaFold monomer V2.0 prediction for methionine synthase reductase (Q8C1A3)
Q8C1A3: “AlphaFold monomer V2.0 prediction for methionine synthase reductase (Q8C1A3)”. 10 pockets (best druggability 0.83). MolNFT v1 #248997 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8C1A3
- Type
- protein
- Length
- 696 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xB44F19a0cb161828322eEEd13F55d4C3C34938d2
- Molecule
- Methionine synthase reductase
- UniProt
- Q8C1A3
- Pockets
- 10 · best druggability 0.83
Structure
1 distinct chain · 36% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Methionine synthase reductase | protein | 696 | 36% helix, 19% strand | Q8C1A3 |
Pockets
10 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 646 | 0.83 | 0.87 | 92 | empty |
| 2 | 116 | 0.64 | 0.88 | 25 | empty |
| 3 | 121 | 0.64 | 0.88 | 20 | empty |
| 4 | 220 | 0.63 | 0.82 | 39 | empty |
| 5 | 81 | 0.58 | 0.88 | 21 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8C1A3
- Elsewhere: UniProt Q8C1A3 · AlphaFold DB Q8C1A3
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