MolNFT v1 · #248842 · protein
AlphaFold monomer V2.0 prediction for melatonin receptor type 1C (P49219)
P49219: “AlphaFold monomer V2.0 prediction for melatonin receptor type 1C (P49219)”. 6 pockets (best druggability 0.83). MolNFT v1 #248842 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P49219
- Type
- protein
- Length
- 420 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xf87a97E0A4bB354D834857B14296240B167cbe70
- Molecule
- Melatonin receptor type 1C
- UniProt
- P49219
- Pockets
- 6 · best druggability 0.83
Structure
1 distinct chain · 65% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Melatonin receptor type 1C | protein | 420 | 65% helix, 2% strand | P49219 |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 196 | 0.83 | 0.97 | 34 | empty |
| 2 | 345 | 0.58 | 0.75 | 32 | empty |
| 3 | 66 | 0.40 | 0.80 | 18 | empty |
| 4 | 55 | 0.37 | 0.80 | 18 | empty |
| 5 | 85 | 0.36 | 0.75 | 15 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P49219
- Elsewhere: UniProt P49219 · AlphaFold DB P49219
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