MolNFT v1 · #248829 · protein

AlphaFold monomer V2.0 prediction for melatonin receptor type 1A (P49217)

P49217: “AlphaFold monomer V2.0 prediction for melatonin receptor type 1A (P49217)”. 5 pockets (best druggability 0.82). MolNFT v1 #248829 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P49217
Type: protein
Length: 353 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x81106a8303497ae2BcdCbBb159a9b5df2f62b627
Molecule: Melatonin receptor type 1A
UniProt: P49217
Pockets: 5 · best druggability 0.82

Structure

1 distinct chain · 73% helix, 2% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Melatonin receptor type 1A	protein	353	73% helix, 2% strand	P49217

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	172	0.82	0.97	28	empty
2	339	0.57	0.76	41	empty
3	130	0.42	0.75	14	empty
4	87	0.37	0.75	14	empty
5	61	0.35	0.78	18	empty

Modifications

Observed in the structure: 2 disulfide (disulfide).

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P49217
Elsewhere: UniProt P49217 · AlphaFold DB P49217

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