MolNFT v1 · #248825 · protein
AlphaFold monomer V2.0 prediction for cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1A (A8XYX2)
A8XYX2: “AlphaFold monomer V2.0 prediction for cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1A (A8XYX2)”. 12 pockets (best druggability 0.76). MolNFT v1 #248825 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A8XYX2
- Type
- protein
- Length
- 874 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xF5183B7F8b5C47bB916c44D76C94a3f60767809e
- Molecule
- Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1A
- UniProt
- A8XYX2
- Pockets
- 12 · best druggability 0.76
Structure
1 distinct chain · 37% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1A | protein | 874 | 37% helix, 18% strand | A8XYX2 |
Pockets
12 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 537 | 0.76 | 0.83 | 42 | empty |
| 2 | 1104 | 0.76 | 0.78 | 81 | empty |
| 3 | 114 | 0.76 | 0.96 | 19 | empty |
| 4 | 163 | 0.65 | 0.86 | 33 | empty |
| 5 | 291 | 0.55 | 0.76 | 34 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A8XYX2
- Elsewhere: UniProt A8XYX2 · AlphaFold DB A8XYX2
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