MolNFT v1 · #248818 · protein
AlphaFold monomer V2.0 prediction for microsomal triglyceride transfer protein large subunit (D4A1W8)
D4A1W8: “AlphaFold monomer V2.0 prediction for microsomal triglyceride transfer protein large subunit (D4A1W8)”. 8 pockets (best druggability 0.87). MolNFT v1 #248818 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- D4A1W8
- Type
- protein
- Length
- 896 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9073C46348542FfE4327c3F363F9B51B22058e75
- Molecule
- Microsomal triglyceride transfer protein large subunit
- UniProt
- D4A1W8
- Pockets
- 8 · best druggability 0.87
Structure
1 distinct chain · 31% helix, 34% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Microsomal triglyceride transfer protein large subunit | protein | 896 | 31% helix, 34% strand | D4A1W8 |
Pockets
8 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1089 | 0.87 | 0.88 | 95 | empty |
| 2 | 949 | 0.82 | 0.84 | 100 | empty |
| 3 | 89 | 0.67 | 0.91 | 23 | empty |
| 4 | 610 | 0.63 | 0.74 | 54 | empty |
| 5 | 130 | 0.57 | 0.83 | 25 | empty |
Modifications
Observed in the structure: 4 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt D4A1W8
- Elsewhere: UniProt D4A1W8 · AlphaFold DB D4A1W8
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