MolNFT v1 · #248814 · protein
AlphaFold monomer V2.0 prediction for microsomal triglyceride transfer protein (A0A0N6WHT4)
A0A0N6WHT4: “AlphaFold monomer V2.0 prediction for microsomal triglyceride transfer protein (A0A0N6WHT4)”. 8 pockets (best druggability 0.84). MolNFT v1 #248814 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A0A0N6WHT4
- Type
- protein
- Length
- 886 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xB11b1b6F67F260bcC019F17cf7691AdaF52aE7B7
- Molecule
- Microsomal triglyceride transfer protein
- Pockets
- 8 · best druggability 0.84
Structure
1 distinct chain · 31% helix, 36% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Microsomal triglyceride transfer protein | protein | 886 | 31% helix, 36% strand | — |
Pockets
8 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 511 | 0.84 | 0.90 | 56 | empty |
| 2 | 714 | 0.83 | 0.86 | 48 | empty |
| 3 | 964 | 0.78 | 0.80 | 98 | empty |
| 4 | 625 | 0.66 | 0.76 | 62 | empty |
| 5 | 149 | 0.56 | 0.82 | 30 | empty |
Modifications
Observed in the structure: 4 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
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