MolNFT v1 · #248719 · protein
AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase mtor (P42346)
P42346: “AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase mtor (P42346)”. 20 pockets (best druggability 0.85). MolNFT v1 #248719 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P42346
- Type
- protein
- Length
- 2,549 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7d626243aF5Ca6d5eB0779378463DcADA09F69c7
- Molecule
- SERINE/THREONINE-protein kinase mtor
- UniProt
- P42346
- Pockets
- 20 · best druggability 0.85
Structure
1 distinct chain · 69% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SERINE/THREONINE-protein kinase mtor | protein | 2549 | 69% helix, 2% strand | P42346 |
Pockets
20 pockets found on a 1 Å grid, 15 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 700 | 0.85 | 0.89 | 70 | empty |
| 2 | 810 | 0.77 | 0.81 | 93 | empty |
| 3 | 860 | 0.72 | 0.77 | 77 | empty |
| 4 | 227 | 0.71 | 0.87 | 33 | empty |
| 5 | 490 | 0.70 | 0.80 | 64 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P42346
- Elsewhere: UniProt P42346 · AlphaFold DB P42346
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