MolNFT v1 · #247383 · protein
AlphaFold monomer V2.0 prediction for methylenetetrahydrofolate reductase (Q60HE5)
Q60HE5: “AlphaFold monomer V2.0 prediction for methylenetetrahydrofolate reductase (Q60HE5)”. 7 pockets (best druggability 0.79). MolNFT v1 #247383 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q60HE5
- Type
- protein
- Length
- 656 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xa73BAb1DabE4333A884D03393eAa10c3B4215494
- Molecule
- Methylenetetrahydrofolate reductase
- UniProt
- Q60HE5
- Pockets
- 7 · best druggability 0.79
Structure
1 distinct chain · 39% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Methylenetetrahydrofolate reductase | protein | 656 | 39% helix, 15% strand | Q60HE5 |
Pockets
7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1138 | 0.79 | 0.81 | 99 | empty |
| 2 | 728 | 0.77 | 0.81 | 63 | empty |
| 3 | 118 | 0.48 | 0.80 | 20 | empty |
| 4 | 78 | 0.43 | 0.80 | 18 | empty |
| 5 | 158 | 0.42 | 0.74 | 22 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q60HE5
- Elsewhere: UniProt Q60HE5 · AlphaFold DB Q60HE5
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