MolNFT v1 · #247379 · protein
AlphaFold monomer V2.0 prediction for methylenetetrahydrofolate reductase 2 (P53128)
P53128: “AlphaFold monomer V2.0 prediction for methylenetetrahydrofolate reductase 2 (P53128)”. 4 pockets (best druggability 0.79). MolNFT v1 #247379 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P53128
- Type
- protein
- Length
- 600 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x2FCae8136DBc761f6F9310fF638e0F8Ad73E2B9d
- Molecule
- Methylenetetrahydrofolate reductase 2
- UniProt
- P53128
- Pockets
- 4 · best druggability 0.79
Structure
1 distinct chain · 44% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Methylenetetrahydrofolate reductase 2 | protein | 600 | 44% helix, 17% strand | P53128 |
Pockets
4 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 782 | 0.79 | 0.82 | 54 | empty |
| 2 | 754 | 0.76 | 0.80 | 60 | empty |
| 3 | 431 | 0.64 | 0.78 | 47 | empty |
| 4 | 305 | 0.60 | 0.78 | 30 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P53128
- Elsewhere: UniProt P53128 · AlphaFold DB P53128
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