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MolNFT v1 · #247058 · protein

AlphaFold monomer V2.0 prediction for metal-response element-binding transcription factor 2 (Q02395)

Q02395: “AlphaFold monomer V2.0 prediction for metal-response element-binding transcription factor 2 (Q02395)”. 7 pockets (best druggability 0.69). MolNFT v1 #247058 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q02395
Type
protein
Length
593 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xccE07Bb1cCcAb5FcC2f1c06b35F43BCa615b5bC8
Molecule
Metal-response element-binding transcription factor 2
UniProt
Q02395
Pockets
7 · best druggability 0.69

Structure

1 distinct chain · 18% helix, 13% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AMetal-response element-binding transcription factor 2protein59318% helix, 13% strandQ02395

Pockets

7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
16620.690.7767empty
22680.590.7929empty
31270.480.7923empty
41480.460.7714empty
51060.380.7519empty

Compared structures

  • 2YT5 · Solution structure of the PHD domain of Metal-response element-binding transcription… · an experimental structure of the same protein · chain A against A, TM-score 0.10
  • 2YT5 · Solution structure of the phd domain of metal-response element-binding transcription… · an experimental structure of the same protein · chain A against A, TM-score 0.10
  • 2EQJ · Solution structure of the TUDOR domain of Metal-response element-binding transcription… · an experimental structure of the same protein · chain A against A, TM-score 0.10
  • 2EQJ · Solution structure of the tudor domain of metal-response element- binding transcription… · an experimental structure of the same protein · chain A against A, TM-score 0.10

Analyse

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