MolNFT v1 · #246976 · protein
AlphaFold monomer V2.0 prediction for bifunctional methylenetetrahydrofolate DEHYDROGENASE/CYCLOHYDROLASE, mitochondrial (P18155)
P18155: “AlphaFold monomer V2.0 prediction for bifunctional methylenetetrahydrofolate DEHYDROGENASE/CYCLOHYDROLASE…”. 4 pockets (best druggability 0.69). MolNFT v1 #246976 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P18155
- Type
- protein
- Length
- 350 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xb4D2d9c96b0D792d0b77e7147D724cc1F801ae58
- Molecule
- Bifunctional methylenetetrahydrofolate DEHYDROGENASE/CYCLOHYDROLASE, mitochondrial
- UniProt
- P18155
- Pockets
- 4 · best druggability 0.69
Structure
1 distinct chain · 37% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Bifunctional methylenetetrahydrofolate DEHYDROGENASE/CYCLOHYDROLASE, mitochondrial | protein | 350 | 37% helix, 15% strand | P18155 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 536 | 0.69 | 0.78 | 57 | empty |
| 2 | 157 | 0.45 | 0.75 | 22 | empty |
| 3 | 53 | 0.38 | 0.80 | 15 | empty |
| 4 | 57 | 0.30 | 0.75 | 16 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P18155
- Elsewhere: UniProt P18155 · AlphaFold DB P18155
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