MolNFT v1 · #246870 · protein
AlphaFold monomer V2.0 prediction for MDM2-binding protein (Q6NRW0)
Q6NRW0: “AlphaFold monomer V2.0 prediction for MDM2-binding protein (Q6NRW0)”. 10 pockets (best druggability 0.72). MolNFT v1 #246870 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q6NRW0
- Type
- protein
- Length
- 860 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x4Ef77Afb5a3D9F41c95Be3227D1CC986CCb61835
- Molecule
- MDM2-binding protein
- UniProt
- Q6NRW0
- Pockets
- 10 · best druggability 0.72
Structure
1 distinct chain · 37% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | MDM2-binding protein | protein | 860 | 37% helix, 14% strand | Q6NRW0 |
Pockets
10 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 758 | 0.72 | 0.78 | 61 | empty |
| 2 | 726 | 0.68 | 0.76 | 71 | empty |
| 3 | 267 | 0.63 | 0.81 | 28 | empty |
| 4 | 59 | 0.52 | 0.87 | 17 | empty |
| 5 | 118 | 0.51 | 0.81 | 15 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6NRW0
- Elsewhere: UniProt Q6NRW0 · AlphaFold DB Q6NRW0
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