MolNFT v1 · #246869 · protein
AlphaFold monomer V2.0 prediction for MDM2-binding protein (Q8BJS8)
Q8BJS8: “AlphaFold monomer V2.0 prediction for MDM2-binding protein (Q8BJS8)”. 11 pockets (best druggability 0.71). MolNFT v1 #246869 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8BJS8
- Type
- protein
- Length
- 894 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x3aFd2E734A81A7F74B5E57D5823327c30169f279
- Molecule
- MDM2-binding protein
- UniProt
- Q8BJS8
- Pockets
- 11 · best druggability 0.71
Structure
1 distinct chain · 33% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | MDM2-binding protein | protein | 894 | 33% helix, 13% strand | Q8BJS8 |
Pockets
11 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 464 | 0.71 | 0.81 | 47 | empty |
| 2 | 555 | 0.69 | 0.79 | 63 | empty |
| 3 | 371 | 0.69 | 0.82 | 43 | empty |
| 4 | 208 | 0.60 | 0.82 | 31 | empty |
| 5 | 163 | 0.49 | 0.77 | 24 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8BJS8
- Elsewhere: UniProt Q8BJS8 · AlphaFold DB Q8BJS8
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