MolNFT v1 · #246651 · protein
AlphaFold monomer V2.0 prediction for N6-adenosine-methyltransferase subunit METTL3 (Q8C3P7)
Q8C3P7: “AlphaFold monomer V2.0 prediction for N6-adenosine-methyltransferase subunit METTL3 (Q8C3P7)”. 6 pockets (best druggability 0.69). MolNFT v1 #246651 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8C3P7
- Type
- protein
- Length
- 580 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x661f92Fc5950020C7aB410B5F5b9a3f429F49Ae5
- Molecule
- N6-adenosine-methyltransferase subunit METTL3
- UniProt
- Q8C3P7
- Pockets
- 6 · best druggability 0.69
Structure
1 distinct chain · 30% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | N6-adenosine-methyltransferase subunit METTL3 | protein | 580 | 30% helix, 15% strand | Q8C3P7 |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 580 | 0.69 | 0.78 | 60 | empty |
| 2 | 121 | 0.56 | 0.83 | 18 | empty |
| 3 | 252 | 0.49 | 0.74 | 28 | empty |
| 4 | 63 | 0.41 | 0.81 | 16 | empty |
| 5 | 144 | 0.41 | 0.74 | 19 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8C3P7
- Elsewhere: UniProt Q8C3P7 · AlphaFold DB Q8C3P7
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