MolNFT v1 · #245006 · protein
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein MSH2 (P25847)
P25847: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein MSH2 (P25847)”. 10 pockets (best druggability 0.81). MolNFT v1 #245006 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P25847
- Type
- protein
- Length
- 964 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x83EA1b9B938A1d5916f949d2c97d793cf032c313
- Molecule
- DNA mismatch repair protein MSH2
- UniProt
- P25847
- Pockets
- 10 · best druggability 0.81
Structure
1 distinct chain · 51% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein MSH2 | protein | 964 | 51% helix, 18% strand | P25847 |
Pockets
10 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1073 | 0.81 | 0.82 | 93 | empty |
| 2 | 292 | 0.68 | 0.83 | 26 | empty |
| 3 | 202 | 0.54 | 0.78 | 24 | empty |
| 4 | 119 | 0.53 | 0.82 | 19 | empty |
| 5 | 185 | 0.47 | 0.75 | 23 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P25847
- Elsewhere: UniProt P25847 · AlphaFold DB P25847
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