MolNFT v1 · #244999 · protein
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein spellchecker 1 (P43248)
P43248: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein spellchecker 1 (P43248)”. 9 pockets (best druggability 0.82). MolNFT v1 #244999 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P43248
- Type
- protein
- Length
- 917 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xBeB220F0B5b0C48F46B5DDd3E3b071BC0827f8D6
- Molecule
- DNA mismatch repair protein spellchecker 1
- UniProt
- P43248
- Pockets
- 9 · best druggability 0.82
Structure
1 distinct chain · 50% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein spellchecker 1 | protein | 917 | 50% helix, 18% strand | P43248 |
Pockets
9 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1068 | 0.82 | 0.83 | 106 | empty |
| 2 | 179 | 0.62 | 0.84 | 32 | empty |
| 3 | 282 | 0.53 | 0.75 | 43 | empty |
| 4 | 74 | 0.44 | 0.81 | 21 | empty |
| 5 | 96 | 0.39 | 0.76 | 19 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P43248
- Elsewhere: UniProt P43248 · AlphaFold DB P43248
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