MolNFT v1 · #243943 · protein
AlphaFold monomer V2.0 prediction for DNA double-strand break repair protein MRE11 (Q8TXI3)
Q8TXI3: “AlphaFold monomer V2.0 prediction for DNA double-strand break repair protein MRE11 (Q8TXI3)”. 4 pockets (best druggability 0.51). MolNFT v1 #243943 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8TXI3
- Type
- protein
- Length
- 451 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x058c4C0f329bb1F8Be9be0DFCbC9073d1000Ba26
- Molecule
- DNA double-strand break repair protein MRE11
- UniProt
- Q8TXI3
- Pockets
- 4 · best druggability 0.51
Structure
1 distinct chain · 28% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA double-strand break repair protein MRE11 | protein | 451 | 28% helix, 21% strand | Q8TXI3 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 237 | 0.51 | 0.75 | 29 | empty |
| 2 | 200 | 0.48 | 0.75 | 25 | empty |
| 3 | 67 | 0.32 | 0.75 | 21 | empty |
| 4 | 62 | 0.26 | 0.72 | 18 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8TXI3
- Elsewhere: UniProt Q8TXI3 · AlphaFold DB Q8TXI3
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