MolNFT v1 · #243900 · protein

AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase mrck alpha (Q5VT25)

Q5VT25: “AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase mrck alpha (Q5VT25)”. 14 pockets (best druggability 0.72). MolNFT v1 #243900 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q5VT25
Type: protein
Length: 1,732 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x0A91570a0CF639a9FD80d9C8cB75c7698aaAD8f1
Molecule: SERINE/THREONINE-protein kinase mrck alpha
UniProt: Q5VT25
Pockets: 14 · best druggability 0.72

Structure

1 distinct chain · 40% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	SERINE/THREONINE-protein kinase mrck alpha	protein	1732	40% helix, 17% strand	Q5VT25

Pockets

14 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	442	0.72	0.82	35	empty
2	403	0.72	0.83	44	empty
3	613	0.67	0.76	54	empty
4	405	0.64	0.78	48	empty
5	249	0.64	0.82	36	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5VT25
Elsewhere: UniProt Q5VT25 · AlphaFold DB Q5VT25

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