MolNFT v1 · #243896 · protein
AlphaFold monomer V2.0 prediction for mediator of replication checkpoint protein 1 (P25588)
P25588: “AlphaFold monomer V2.0 prediction for mediator of replication checkpoint protein 1 (P25588)”. 2 pockets (best druggability 0.30). MolNFT v1 #243896 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P25588
- Type
- protein
- Length
- 1,096 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x97EfFf2d74994e28D3b69b1503Bd9c292B2Df480
- Molecule
- Mediator of replication checkpoint protein 1
- UniProt
- P25588
- Pockets
- 2 · best druggability 0.30
Structure
1 distinct chain · 28% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Mediator of replication checkpoint protein 1 | protein | 1096 | 28% helix, 0% strand | P25588 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 50 | 0.30 | 0.76 | 11 | empty |
| 2 | 64 | 0.27 | 0.72 | 15 | empty |
Compared structures
- 8B9B · S. cerevisiae replisome + Ctf4, bound by pol alpha. Complex engaged with a fork DNA… · an experimental structure of the same protein · chain A against P, TM-score 0.02
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P25588
- Elsewhere: UniProt P25588 · AlphaFold DB P25588
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