MolNFT v1 · #242221 · protein
AlphaFold monomer V2.0 prediction for mitogen-activated protein kinase 8 (Q5SN53)
Q5SN53: “AlphaFold monomer V2.0 prediction for mitogen-activated protein kinase 8 (Q5SN53)”. 12 pockets (best druggability 0.81). MolNFT v1 #242221 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q5SN53
- Type
- protein
- Length
- 569 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x605d3052093391F2D57b33217931db4627F892dC
- Molecule
- Mitogen-activated protein kinase 8
- UniProt
- Q5SN53
- Pockets
- 12 · best druggability 0.81
Structure
1 distinct chain · 32% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Mitogen-activated protein kinase 8 | protein | 569 | 32% helix, 9% strand | Q5SN53 |
Pockets
12 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1051 | 0.81 | 0.82 | 82 | empty |
| 2 | 50 | 0.55 | 0.90 | 14 | empty |
| 3 | 117 | 0.53 | 0.82 | 16 | empty |
| 4 | 82 | 0.49 | 0.83 | 17 | empty |
| 5 | 234 | 0.49 | 0.75 | 32 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5SN53
- Elsewhere: UniProt Q5SN53 · AlphaFold DB Q5SN53
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