MolNFT v1 · #242201 · protein
AlphaFold monomer V2.0 prediction for mitogen-activated protein kinase mpk-1 (P39745)
P39745: “AlphaFold monomer V2.0 prediction for mitogen-activated protein kinase mpk-1 (P39745)”. 7 pockets (best druggability 0.70). MolNFT v1 #242201 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P39745
- Type
- protein
- Length
- 444 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x0D671490EE06E75975e90D7F99F73B20BE618744
- Molecule
- Mitogen-activated protein kinase mpk-1
- UniProt
- P39745
- Pockets
- 7 · best druggability 0.70
Structure
1 distinct chain · 34% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Mitogen-activated protein kinase mpk-1 | protein | 444 | 34% helix, 13% strand | P39745 |
Pockets
7 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 363 | 0.70 | 0.83 | 41 | empty |
| 2 | 61 | 0.43 | 0.82 | 18 | empty |
| 3 | 131 | 0.42 | 0.75 | 16 | empty |
| 4 | 109 | 0.40 | 0.76 | 24 | empty |
| 5 | 78 | 0.32 | 0.74 | 16 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P39745
- Elsewhere: UniProt P39745 · AlphaFold DB P39745
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