MolNFT v1 · #242185 · protein
AlphaFold monomer V2.0 prediction for mitogen-activated protein kinase 12 (Q8GYQ5)
Q8GYQ5: “AlphaFold monomer V2.0 prediction for mitogen-activated protein kinase 12 (Q8GYQ5)”. 3 pockets (best druggability 0.76). MolNFT v1 #242185 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8GYQ5
- Type
- protein
- Length
- 372 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x121FBE8cb498Fefb77e8499d91A1200302f3Fc6b
- Molecule
- Mitogen-activated protein kinase 12
- UniProt
- Q8GYQ5
- Pockets
- 3 · best druggability 0.76
Structure
1 distinct chain · 37% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Mitogen-activated protein kinase 12 | protein | 372 | 37% helix, 17% strand | Q8GYQ5 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 572 | 0.76 | 0.83 | 57 | empty |
| 2 | 58 | 0.38 | 0.80 | 19 | empty |
| 3 | 63 | 0.32 | 0.76 | 14 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8GYQ5
- Elsewhere: UniProt Q8GYQ5 · AlphaFold DB Q8GYQ5
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