MolNFT v1 · #242120 · protein
AlphaFold monomer V2.0 prediction for ATP-dependent DNA helicase MPH1 (P40562)
P40562: “AlphaFold monomer V2.0 prediction for ATP-dependent DNA helicase MPH1 (P40562)”. 8 pockets (best druggability 0.77). MolNFT v1 #242120 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P40562
- Type
- protein
- Length
- 993 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x0956BbcA81771e19889F6414c9873Eda5474b334
- Molecule
- ATP-dependent DNA helicase MPH1
- UniProt
- P40562
- Pockets
- 8 · best druggability 0.77
Structure
1 distinct chain · 42% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | ATP-dependent DNA helicase MPH1 | protein | 993 | 42% helix, 11% strand | P40562 |
Pockets
8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1103 | 0.77 | 0.79 | 105 | empty |
| 2 | 853 | 0.74 | 0.79 | 79 | empty |
| 3 | 167 | 0.57 | 0.81 | 23 | empty |
| 4 | 132 | 0.39 | 0.73 | 21 | empty |
| 5 | 55 | 0.33 | 0.77 | 13 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P40562
- Elsewhere: UniProt P40562 · AlphaFold DB P40562
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.