MolNFT v1 · #242021 · protein
AlphaFold monomer V2.0 prediction for protein disulfide-isomerase MPD1 (Q12404)
Q12404: “AlphaFold monomer V2.0 prediction for protein disulfide-isomerase MPD1 (Q12404)”. 3 pockets (best druggability 0.56). MolNFT v1 #242021 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q12404
- Type
- protein
- Length
- 318 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x940bB0965EeFe24d3893a6Bf34f0F4F8890dF048
- Molecule
- Protein disulfide-isomerase MPD1
- UniProt
- Q12404
- Pockets
- 3 · best druggability 0.56
Structure
1 distinct chain · 36% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein disulfide-isomerase MPD1 | protein | 318 | 36% helix, 16% strand | Q12404 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 165 | 0.56 | 0.81 | 26 | empty |
| 2 | 181 | 0.49 | 0.77 | 29 | empty |
| 3 | 58 | 0.26 | 0.73 | 14 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 3ED3 · Crystal Structure of the Yeast Dithiol/Disulfide Oxidoreductase Mpd1p · an experimental structure of the same protein · chain A against A, TM-score 0.84
- 3ED3 · Crystal structure of the yeast DITHIOL/DISULFIDE oxidoreductase MPD1P · an experimental structure of the same protein · chain A against A, TM-score 0.84
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q12404
- Elsewhere: UniProt Q12404 · AlphaFold DB Q12404
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