MolNFT v1 · #241866 · protein
AlphaFold monomer V2.0 prediction for dual specificity mitogen- activated protein kinase kinase 2 (Q1HG70)
Q1HG70 · Dual specificity mitogen-activated protein kinase kinase 2: “AlphaFold monomer V2.0 prediction for dual specificity mitogen- activated protein kinase kinase 2 (Q1HG70)”. 5 pockets (best druggability 0.78). MolNFT v1 #241866 on…
- Accession
- Q1HG70
- Type
- protein
- Length
- 400 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x1ED4a68B4011314730adE976b56Ad4cA21b54dcD
- Molecule
- Dual specificity mitogen-activated protein kinase kinase 2
- UniProt
- Q1HG70
- Pockets
- 5 · best druggability 0.78
Structure
1 distinct chain · 40% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Dual specificity mitogen-activated protein kinase kinase 2 | protein | 400 | 40% helix, 12% strand | Q1HG70 |
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1120 | 0.78 | 0.80 | 100 | empty |
| 2 | 385 | 0.67 | 0.80 | 45 | empty |
| 3 | 199 | 0.48 | 0.75 | 24 | empty |
| 4 | 199 | 0.48 | 0.75 | 26 | empty |
| 5 | 109 | 0.42 | 0.77 | 17 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q1HG70
- Elsewhere: UniProt Q1HG70 · AlphaFold DB Q1HG70
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