MolNFT v1 · #241861 · protein
AlphaFold monomer V2.0 prediction for dual specificity mitogen- activated protein kinase kinase 1 (Q9XT09)
Q9XT09 · Dual specificity mitogen-activated protein kinase kinase 1: “AlphaFold monomer V2.0 prediction for dual specificity mitogen- activated protein kinase kinase 1 (Q9XT09)”. 7 pockets (best druggability 0.78). MolNFT v1 #241861 on…
- Accession
- Q9XT09
- Type
- protein
- Length
- 393 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xf4ED13986579E8e227b3ED6c02276c648754EC27
- Molecule
- Dual specificity mitogen-activated protein kinase kinase 1
- UniProt
- Q9XT09
- Pockets
- 7 · best druggability 0.78
Structure
1 distinct chain · 41% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Dual specificity mitogen-activated protein kinase kinase 1 | protein | 393 | 41% helix, 12% strand | Q9XT09 |
Pockets
7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 846 | 0.78 | 0.81 | 84 | empty |
| 2 | 475 | 0.65 | 0.77 | 46 | empty |
| 3 | 149 | 0.65 | 0.86 | 24 | empty |
| 4 | 157 | 0.49 | 0.78 | 27 | empty |
| 5 | 227 | 0.47 | 0.74 | 31 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9XT09
- Elsewhere: UniProt Q9XT09 · AlphaFold DB Q9XT09
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