MolNFT v1 · #241720 · protein
AlphaFold monomer V2.0 prediction for proto-oncogene SERINE/THREONINE-protein kinase mos (P00539)
P00539: “AlphaFold monomer V2.0 prediction for proto-oncogene SERINE/THREONINE-protein kinase mos (P00539)”. 4 pockets (best druggability 0.65). MolNFT v1 #241720 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P00539
- Type
- protein
- Length
- 339 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x1C6d74B24246Fb79541e3b0466c2b0D0b51a2553
- Molecule
- Proto-oncogene SERINE/THREONINE-protein kinase mos
- UniProt
- P00539
- Pockets
- 4 · best druggability 0.65
Structure
1 distinct chain · 36% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Proto-oncogene SERINE/THREONINE-protein kinase mos | protein | 339 | 36% helix, 16% strand | P00539 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 283 | 0.65 | 0.82 | 30 | empty |
| 2 | 500 | 0.63 | 0.76 | 46 | empty |
| 3 | 79 | 0.34 | 0.75 | 15 | empty |
| 4 | 86 | 0.31 | 0.73 | 19 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00539
- Elsewhere: UniProt P00539 · AlphaFold DB P00539
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