MolNFT v1 · #241715 · protein
AlphaFold monomer V2.0 prediction for proto-oncogene SERINE/THREONINE-protein kinase mos (P00540)
P00540: “AlphaFold monomer V2.0 prediction for proto-oncogene SERINE/THREONINE-protein kinase mos (P00540)”. 4 pockets (best druggability 0.69). MolNFT v1 #241715 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P00540
- Type
- protein
- Length
- 346 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x0FaaD3fBa5c3c3BDB4B7FcB93FbBE64552D63Ea8
- Molecule
- Proto-oncogene SERINE/THREONINE-protein kinase mos
- UniProt
- P00540
- Pockets
- 4 · best druggability 0.69
Structure
1 distinct chain · 36% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Proto-oncogene SERINE/THREONINE-protein kinase mos | protein | 346 | 36% helix, 15% strand | P00540 |
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 459 | 0.69 | 0.80 | 41 | empty |
| 2 | 302 | 0.57 | 0.77 | 40 | empty |
| 3 | 202 | 0.52 | 0.77 | 27 | empty |
| 4 | 127 | 0.41 | 0.75 | 19 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00540
- Elsewhere: UniProt P00540 · AlphaFold DB P00540
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